Strategies for targeting primate neural circuits with viral vectors
نویسندگان
چکیده
منابع مشابه
Strategies for targeting primate neural circuits with viral vectors.
Understanding how the brain works requires understanding how different types of neurons contribute to circuit function and organism behavior. Progress on this front has been accelerated by optogenetics and chemogenetics, which provide an unprecedented level of control over distinct neuronal types in small animals. In primates, however, targeting specific types of neurons with these tools remain...
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Optogenetic methodology enables direct targeting of specific neural circuit elements for inhibition or excitation while spanning timescales from the acute (milliseconds) to the chronic (many days or more). Although the impact of this temporal versatility and cellular specificity has been greater for basic science than clinical research, it is natural to ask whether the dynamic patterns of neura...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2016
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00087.2016